Toxoplasma F-box protein 1 is required for daughter cell scaffold function during parasite replication.
By binding to the adaptor protein SKP1 and serving as substrate receptors for the SKP1 Cullin, F-box E3 ubiquitin ligase complex, F-box proteins regulate critical cellular processes including cell cycle progression and membrane trafficking.While F-box proteins are conserved throughout eukaryotes and are well studied in yeast, plants, and animals, s